Bone marrow, a soft as well as spongy tissue inside the bones, helps for the production of hematopoietic stem cells which help to develop health RBC, WBC, and platelets. The bone marrow transplant in India treatment procedure is made for the replacement of stem cells which are cancerous, defected and damaged by the radiation process or chemotherapy.
Reasons for bone marrow transplantation
- Sometimes, bone marrows get damaged by the high doses of radiation treatment or chemotherapy.
- Replacement of diseased or destroyed bone marrow by the new stem cells.
- New stem cells are provided to destroy the cancerous cells.
- Transplantation of bone marrows can be made for the treatment of cancerous as well as the noncancerous diseases like Acuteleukemia, Aplastic anemia, Chronic leukemia, Adrenoleukodystrophy, Syndromes for the failure of bone marrow, inborn errors of metabolism, immune deficiencies, multiple myeloma, Hodgkin’s lymphoma, neuroblastoma, a disorder of plasma cells.
Tests and procedures before making the bone marrow transplantation
A series of tests and process are made for the assessment of general health condition and it has to be ensured that you are completely physically prepared for the bone marrow transplantation. Moreover, the surgeon makes the implantation of a large vein in your neck or chest. The catheter or central line is made to infuse the transplanted stem cells by using the central line and it also used for medication or blood product.
Collection of stem cell for making the transplantation procedure
Apheresis procedure is made when your own stem cells are used for the transplantation, which is known as autologous transplantation.Before making the apheresis, you will have to take injections to influence the growth factor for increasing the production of stem cells and making the movement of stem cells into the blood circulatory system for collection of stem cells. For making the apheresis procedure, blood is drawn out from the veins and circulation is continuing through the machine. The machine helps to separate your blood into the various parts of your body including the stem cells. The collection of stem cells is made and stem cells are stored in a frozen state for the use in future transplantation. The return of your remaining blood is transferred to your body. When the transplantation procedure is made by a donor, the procedure is known as allogeneic transplantation. The team for transplantation will take the decision which will be suitable for you according to your condition. There is one more type of allogeneic transplantation which is made by using the stem cells of the blood from the umbilical cords. Mother will have the choice for the donation of the umbilical cord after the birth of her baby. These stem cells are also can be frozen for future bone marrow transplantation.
The condition is made for making the procedure of bone transplantation
At the time of condition period, the chemotherapy and possible method of radiation are made to destroy the cancerous cells if you have the treatment for malignancy, suppression of your immune system. Make the preparation of bone marrow for the benefits of new stem cells.